Nature Communications (Feb 2022)
Colocalized, bidirectional optogenetic modulations in freely behaving mice with a wireless dual-color optoelectronic probe
- Lizhu Li,
- Lihui Lu,
- Yuqi Ren,
- Guo Tang,
- Yu Zhao,
- Xue Cai,
- Zhao Shi,
- He Ding,
- Changbo Liu,
- Dali Cheng,
- Yang Xie,
- Huachun Wang,
- Xin Fu,
- Lan Yin,
- Minmin Luo,
- Xing Sheng
Affiliations
- Lizhu Li
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Lihui Lu
- Chinese Institute for Brain Research
- Yuqi Ren
- Chinese Institute for Brain Research
- Guo Tang
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Yu Zhao
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Xue Cai
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Zhao Shi
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- He Ding
- School of Optics and Photonics, Beijing Institute of Technology
- Changbo Liu
- School of Materials Science and Engineering, Beihang University
- Dali Cheng
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Yang Xie
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Huachun Wang
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- Xin Fu
- School of Materials Science and Engineering, Tsinghua University
- Lan Yin
- School of Materials Science and Engineering, Tsinghua University
- Minmin Luo
- Chinese Institute for Brain Research
- Xing Sheng
- Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Center for Flexible Electronics Technology, Tsinghua University
- DOI
- https://doi.org/10.1038/s41467-022-28539-7
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 14
Abstract
Simultaneous neural activation and inhibition in the same brain region of animals is highly desirable. Here the authors report a wireless, dual-colour optogenetic probe with the co-expression of two spectrally distinct opsins to allow for bidirectional neuronal activity manipulation in a rodent model.
