(23R,231S,25S)-231,26-Epoxy-23-ethylfurost-20(22)-en-3β-ol

Abstract

The title compound, C29H46O3, is a steroid synthesized through a rearrangement of a sarsasapogenin derivative in acidic medium. The newly formed ring F is a tetrahydro-2H-pyran heterocycle substituted by two methyl groups placed in equatorial positions. This ring displays a chair conformation, while dihydrofuran ring E, to which it is bonded, has an envelope conformation. The molecules are associated by weak O—H...O hydrogen bonds to form chains running in the [101] direction in the crystal.

Keywords

• crystal structure
• tetrahydropyran
• sarsasapogenin
• rearrangement reaction
• hydrogen bond