Clinical Medicine Insights: Gastroenterology (Jan 2011)

Once-Daily MMX Mesalamine in the Management of Ulcerative colitis

  • Wojciech Blonski,
  • Anna M. Buchner,
  • Gary R. Lichtenstein

DOI
https://doi.org/10.4137/CGast.S4276
Journal volume & issue
Vol. 4

Abstract

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Mesalamine (5-ASA) has been the mainstay therapy of mild to moderate active ulcerative colitis both as an induction and maintenance treatment. Multimatrix system (MMX) 5-ASA is a recently developed formulation of 5-ASA allowing for slow and gradual release of 5-ASA throughout the entire colon. This review article discusses the structure, pharmacokinetics, efficacy and safety of this new 5-ASA formulation.