Emerging Infectious Diseases (Feb 2013)

Human Granulocytic Anaplasmosis, Japan

  • Norio Ohashi,
  • Gaowa,
  • Wuritu,
  • Fumihiko Kawamori,
  • Dongxing Wu,
  • Yuko Yoshikawa,
  • Seizou Chiya,
  • Kazutoshi Fukunaga,
  • Toyohiko Funato,
  • Masaaki Shiojiri,
  • Hideki Nakajima,
  • Yoshiji Hamauzu,
  • Ai Takano,
  • Hiroki Kawabata,
  • Shuji Ando,
  • Toshio Kishimoto

DOI
https://doi.org/10.3201/eid1902.120855
Journal volume & issue
Vol. 19, no. 2
pp. 289 – 292

Abstract

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We retrospectively confirmed 2 cases of human Anaplasma phagocytophilum infection. Patient blood samples contained unique p44/msp2 for the pathogen, and antibodies bound to A. phagocytophilum antigens propagated in THP-1 rather than HL60 cells. Unless both cell lines are used for serodiagnosis of rickettsiosis-like infections, cases of human granulocytic anaplasmosis could go undetected.

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