Nature Communications (May 2019)

Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method

  • Weitian Zhao,
  • David Michalik,
  • Stephen Ferguson,
  • Willy Hofstetter,
  • Jacques Lemaître,
  • Brigitte von Rechenberg,
  • Paul Bowen

DOI
https://doi.org/10.1038/s41467-019-09673-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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In vitro testing of implant materials bioactivity is important and the current methods take time. Here, the authors report on the development of a faster titration based method for assessing the mineralization activity of materials and validate the method in vitro and in vivo using titanium surfaces.