The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains

Paweł Kwiatkowski; Łukasz Łopusiewicz; Mateusz Kostek; Emilia Drozłowska; Agata Pruss; Bartosz Wojciuk; Monika Sienkiewicz; Hanna Zielińska-Bliźniewska; Barbara Dołęgowska

doi:10.3390/molecules25010095

Molecules (Dec 2019)

The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains

Paweł Kwiatkowski,
Łukasz Łopusiewicz,
Mateusz Kostek,
Emilia Drozłowska,
Agata Pruss,
Bartosz Wojciuk,
Monika Sienkiewicz,
Hanna Zielińska-Bliźniewska,
Barbara Dołęgowska

Affiliations

Paweł Kwiatkowski: Department of Diagnostic Immunology, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, 72 Powstańców Wielkopolskich Avenue, 70-111 Szczecin, Poland
Łukasz Łopusiewicz: Center of Bioimmobilisation and Innovative Packaging Materials, Faculty of Food Sciences and Fisheries, West Pomeranian University of Technology Szczecin, Janickiego 35, 71-270 Szczecin, Poland
Mateusz Kostek: Department of Diagnostic Immunology, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, 72 Powstańców Wielkopolskich Avenue, 70-111 Szczecin, Poland
Emilia Drozłowska: Center of Bioimmobilisation and Innovative Packaging Materials, Faculty of Food Sciences and Fisheries, West Pomeranian University of Technology Szczecin, Janickiego 35, 71-270 Szczecin, Poland
Agata Pruss: Department of Laboratory Medicine, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, 72 Powstańców Wielkopolskich Avenue, 70-111 Szczecin, Poland
Bartosz Wojciuk: Department of Diagnostic Immunology, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, 72 Powstańców Wielkopolskich Avenue, 70-111 Szczecin, Poland
Monika Sienkiewicz: Department of Allergology and Respiratory Rehabilitation, Medical University of Łódź, Żeligowskiego 7/9, 90-752 Łódź, Poland
Hanna Zielińska-Bliźniewska: Department of Allergology and Respiratory Rehabilitation, Medical University of Łódź, Żeligowskiego 7/9, 90-752 Łódź, Poland
Barbara Dołęgowska: Department of Laboratory Medicine, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, 72 Powstańców Wielkopolskich Avenue, 70-111 Szczecin, Poland

DOI: https://doi.org/10.3390/molecules25010095
Journal volume & issue: Vol. 25, no. 1
p. 95

Abstract

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In the post-antibiotic era the issue of bacterial resistance refers not only to antibiotics themselves but also to common antiseptics like octenidine dihydrochloride (OCT). This appears as an emerging challenge in terms of preventing staphylococcal infections, which are both potentially severe and easy to transfer horizontally. Essential oils have shown synergisms both with antibiotics and antiseptics. Therefore the aim of this study was to investigate the impact of lavender essential oil (LEO) on OCT efficiency towards methicillin-resistant S. aureus strains (MRSA). The LEO analyzed in this study increased the OCT’s susceptibility against MRSA strains. Subsequent FTIR analysis revealed cellular wall modifications in MRSA strain cultured in media supplemented with OCT or LEO/OCT. In conclusion, LEO appears to be a promising candidate for an efficient enhancer of conventional antiseptics.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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