Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells showing intraductal growth and intratumoral hemorrhage: MRI features

Keisuke Sato, MD; Hiroshi Urakawa, MD; Keiko Sakamoto, MD; Emi Ito, MD; Yoshihiro Hamada, MD; Kengo Yoshimitsu, MD, PhD

Radiology Case Reports (Oct 2019)

Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells showing intraductal growth and intratumoral hemorrhage: MRI features

Keisuke Sato, MD,
Hiroshi Urakawa, MD,
Keiko Sakamoto, MD,
Emi Ito, MD,
Yoshihiro Hamada, MD,
Kengo Yoshimitsu, MD, PhD

Affiliations

Keisuke Sato, MD: Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka-shi, Fukuoka 814-0180, Japan
Hiroshi Urakawa, MD: Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka-shi, Fukuoka 814-0180, Japan
Keiko Sakamoto, MD: Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka-shi, Fukuoka 814-0180, Japan
Emi Ito, MD: Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka-shi, Fukuoka 814-0180, Japan
Yoshihiro Hamada, MD: Department of Pathology, Fukuoka University Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka-shi, Fukuoka 814-0180, Japan
Kengo Yoshimitsu, MD, PhD: Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka-shi, Fukuoka 814-0180, Japan; Corresponding author.

Journal volume & issue: Vol. 14, no. 10
pp. 1283 – 1287

Abstract

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We report a case of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells ocalized within the main pancreatic duct (MPD). A 61-year-old woman was referred to our hospital for evaluation of dilatation of the MPD that was detected on screening sonogram. Preoperative MR imaging revealed a small hypervascular tumor within the dilated MPD, showing high signal on R2* map and signal reduction on in-phase as compared to out-of-phase. R2* hyperintensity and in-phase signal reduction may be a characteristic feature of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells, which indicates intratumoral hemorrhage even if they are small. Keywords: Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells, Intratumoral hemorrhage, Intraductal growth, R2* map, Chemical-shift imaging

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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