Primary amyloidosis presenting intrahepatic cholestasis and fulminant hepatic failure

Abstract

A 69-year-old man noticed abdominal pain located on right upper quadrant. Physical examination showed hepatosplenomegaly and icteric discoloration of sclera. On evaluation, patient was diagnosed to have hepatic amyloidosis related monoclonal gammopathy of undetermined significance (MGUS) and sinusoidal obstruction syndrome with intrahepatic cholestasis. In this case report we emphasize fulminant hepatic failure due to primer amyloidosis in diagnosed with MGUS patient.

Keywords

• Fulminant hepatic failure
• primary amyloidosis
• intrahepatic cholestasis
• monoclonal gammopathy of undetermined significance
• sinusoidal obstruction syndrome.