COMPLETE RESPONSE IN SYNCHRONOUS EARLY BREAST AND LUNG CANCER

Abstract

This is a rare case of multiple primary malignancies (MPM) both diagnosed in early stage, for which the patient received multidisciplinary complex treatment and achieved no evidence of disease state. We present a 67-year-old woman admitted in the Department of General surgery, Alexandrovska University Hospital, in April 2017 and diagnosed with invasive ductal carcinoma in the inner lower quadrant of the right breast. During the detailed staging process was found also 2 cm adenocarcinoma in the left lung. The patient underwent upper left lobectomy as a single treatment for lung cancer and received neoadjuvant chemotherapy with Docetaxel, Trastuzumab, and Pertuzumab for breast cancer. After the performed breast-conserving surgery, the final pathological report showed pathologic complete response (pCR). The current treatment modalities provide prolongation of patients’ life, which will increase the rate of MPM. Excellent prognosis still can be achieved when the right management of the patient is applied.

Keywords

• multiple primary malignances
• breast cancer
• pathologic complete response