Nature Communications (Jul 2017)

Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses

  • Kasumi Inokuchi,
  • Fumiaki Imamura,
  • Haruki Takeuchi,
  • Ryang Kim,
  • Hiroyuki Okuno,
  • Hirofumi Nishizumi,
  • Haruhiko Bito,
  • Takefumi Kikusui,
  • Hitoshi Sakano

DOI
https://doi.org/10.1038/ncomms15977
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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Neuropilin 2 (Nrp2) is expressed by a subset of mitral cells in the postero-ventral olfactory bulb in mice. Here the authors show that Nrp2 is sufficient to instruct mitral cell targeting to the anterior part of medial amygdala that modulates olfactory-driven attractive social behaviour.