Songklanakarin Journal of Science and Technology (SJST) (Jul 2003)

HIV-1 protease inhibitory substances from the rhizomes of Boesenbergia pandurata Holtt.

  • Tassanee Panphadung,
  • Jindaporn Puripattanavong,
  • Sanan Subhadhirasakul,
  • Supinya Tewtrakul

Journal volume & issue
Vol. 25, no. 4
pp. 503 – 508

Abstract

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Four flavonoids (pinostrobin, pinocembrin, cardamonin and alpinetin) isolated from the ethanol extract of Boesenbergia pandurata Holtt. (yellow rhizome) were tested for their activities against HIV-1 protease (HIV-PR). The result showed that cardamonin exhibited an appreciable anti-HIV-1 PR activity with an IC50 value of 31 μg/ml.

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