Shipin Kexue (Aug 2024)

Biological Reduction of Heavy Metal Lead by Lactobacillus plantarum CCFM8661

  • LIU Yang, ZHANG Tingting, ZHANG Yonggang, ZHANG Yanmin, HAN Hongyu, WANG Wei, DONG Xueqian

DOI
https://doi.org/10.7506/spkx1002-6630-20230912-104
Journal volume & issue
Vol. 45, no. 15
pp. 112 – 117

Abstract

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Objective: To evaluate the effect of Lactobacillus plantarum CCFM8661 on reducing lead in the human body and its effect on human health. Methods: In total, 60 volunteers suffering from foodborne heavy metal exposure were recruited and divided into two groups, with one orally receiving L. plantarum CCFM8661 powder and the other orally receiving a placebo. The protective effect of L. plantarum CCFM8661 on lead-exposed populations was evaluated comprehensively by analyzing the volunteers’ blood lead levels, blood cells, blood biochemical indexes, serum calcium and iron levels before and after interventions. Results: L. plantarum CCFM8661 intervention effectively reduced the blood lead level in the lead-exposed population, and down-regulated total bilirubin, urea and total serum protein while having no significant effect on blood cells, blood calcium or iron levels. Conclusion: L. plantarum CCFM8661 could protect lead-exposed subjects by effectively reducing lead levels and, thereby, has the potential to be further developed into a biological agent for the bioreduction of heavy metals.

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