Research progress on anti-carbamylated protein antibodies in connective tissue disease

Abstract

Connective tissue disease （CTD） is a group of chronic autoimmune diseases characterized by pathological changes in systemic organs and multisystems. The diagnosis of CTD mainly depends on clinical manifestations and specific autoantibodies. As a newly discovered autoantibody in recent years， anti-carbamylated protein （anti-CarP） antibodies play an important role in the diagnosis， stratification and treatment evaluation of various CTDs. This article reviews the research progress on anti-CarP antibodies in CTD.

Keywords

• |anti-carbamylated protein antibodies|connective tissue disease|rheumatoid arthritis|systemic lupus erythematosus|systemic sclerosis|sjögren’s syndrome