Congenital Microphthalmia with Orbital Cyst: A Case Series

Abstract

Microphthalmos results from incomplete invagination of the optic vesicle or closure of the embryonic fissure. We present three patients with unilateral congenital microphthalmia with cyst. None of them had vision in the affected eye since birth, with gradually increasing mass encroaching towards lower fornix and lower eyelid ectropion. On examination and investigations, patients had large orbital cyst with microphthalmia pushing the eyeball superiorly and posteriorly in affected orbit. Microphthalmic globe with cyst was surgically excised and histopathologically studied. Orbital cavity was big enough to occupy the conformer and the prosthetic eye after 6 weeks. Diagnosis was confirmed by large communicating orbital cyst with microphthalmia without systemic association in all the patients. None of the mothers of patients had (antenatal care) ANC check up. All the parents had consanguineous marriage. ANC check up with ultrasound at 14-16 weeks of pregnancy is important for genetic counselling.

Keywords

• congenital anomaly; cyst; eye; microphthalmos.