Iatreia (Oct 2014)

Severe neurotoxicity due to cefepime in a kidney transplanted patient: case report

  • Aristizabal-Alzate, Arbey ,
  • Nieto-Ríos, John Fredy ,
  • Serna-Higuita, Lina María ,
  • Ocampo-Kohn, Catalina ,
  • Sánchez-Sánchez, Huber Adolfo ,
  • Zuluaga-Valencia, Gustavo Adolfo

Journal volume & issue
Vol. 27, no. 4
pp. 460 – 464

Abstract

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Cefepime is a betalactamic antibiotic used for the treatment of patients with severe infections. It is mainly excreted by the kidney, so that its half-life is significantly increased in patients with kidney failure, and in this population adverse effects may be more severe including neurotoxicity. We report the case of a kidney-transplanted patient who presented neurotoxicity associated with the use of cefepime.

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