DNA origami single crystals with Wulff shapes

Yong Wang; Lizhi Dai; Zhiyuan Ding; Min Ji; Jiliang Liu; Hang Xing; Xiaoguo Liu; Yonggang Ke; Chunhai Fan; Peng Wang; Ye Tian

doi:10.1038/s41467-021-23332-4

Nature Communications (May 2021)

DNA origami single crystals with Wulff shapes

Yong Wang,
Lizhi Dai,
Zhiyuan Ding,
Min Ji,
Jiliang Liu,
Hang Xing,
Xiaoguo Liu,
Yonggang Ke,
Chunhai Fan,
Peng Wang,
Ye Tian

Affiliations

Yong Wang: National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University
Lizhi Dai: National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University
Zhiyuan Ding: National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University
Min Ji: National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University
Jiliang Liu: National Light Source II, Brookhaven National Laboratory
Hang Xing: Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University
Xiaoguo Liu: School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, and Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine, Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Yonggang Ke: Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
Chunhai Fan: School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, and Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine, Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Peng Wang: National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University
Ye Tian: National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University

DOI: https://doi.org/10.1038/s41467-021-23332-4
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 8

Abstract

Read online

DNA origami is a valuable tool for precise manipulation of molecules in a three dimensional manner, but the design and assembly of origami units into single crystals is challenging. Here, the authors report successful fabrication of DNA origami single crystals with Wulff shapes, and regulation of their shapes by changing the symmetry and binding modes of DNA origami building blocks.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal