West Nile Virus infection in a renal transplant recipient resulting in polioencephalomylelitis, quadriplegia, and global brain atrophy

Kamran Kadkhoda; John M. Embil; Lundy R. McKibbin; James McEachern; Michael A. Drebot

IDCases (Jan 2019)

West Nile Virus infection in a renal transplant recipient resulting in polioencephalomylelitis, quadriplegia, and global brain atrophy

Kamran Kadkhoda,
John M. Embil,
Lundy R. McKibbin,
James McEachern,
Michael A. Drebot

Affiliations

Kamran Kadkhoda: Immunopathology Laboratory, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA; Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Corresponding author at: Robert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, 10300 Carnegie Ave. LL3-150, Cleveland, OH, 44106, USA.
John M. Embil: Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Internal Medicine, Section of Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
Lundy R. McKibbin: Department of Internal Medicine, Section of General Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
James McEachern: Department of Diagnostic Imaging, Health Sciences Centre, Winnipeg, Manitoba, Canada
Michael A. Drebot: Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

Journal volume & issue: Vol. 17

Abstract

Read online

An immunosuppressed man developed rapidly progressive neurologic symptoms resulting in quadriplegia. On magnetic resonance imaging multiple areas of abnormal enhancement were observed in the brain, and spinal cord. Serologic evidence of West Nile Virus (WNV) was discovered in the cerebrospinal fluid. This report highlights the catastrophic complications of WNV in an immunocompromised host. Keywords: West Nile Virus, Immunocompromised, Quadriplegia, Encephalomyelitis, Renal transplant

Published in IDCases

ISSN: 2214-2509 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: http://www.journals.elsevier.com/idcases/

About the journal