Brazilian Neurosurgery (Dec 2024)

Perspective on the Influence of Biopsy on the Survival of Pediatric Patients with Diffuse Brainstem Gliomas: A Literature Review

  • Ádria Gabrielle Biondi-Soares,
  • Luís Gustavo Biondi-Soares,
  • Felipe Salvagni Pereira,
  • Willian Pegoraro Kus,
  • Ludimila Brito Batista,
  • Cleiton Formentin

DOI
https://doi.org/10.1055/s-0044-1795072
Journal volume & issue
Vol. 43, no. 04
pp. e319 – e324

Abstract

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Introduction Diffuse brainstem gliomas (DBG) represent the most common subtype of pediatric brainstem tumors, characterized by a systematically grim prognosis with a median survival rate of 10% two years post-diagnosis. Unlike other brain tumors, diffuse brainstem gliomas have traditionally relied on cranial magnetic resonance imaging (MRI) as a sufficient diagnostic tool, rendering surgical biopsies deemed unnecessary.

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