Diagnosis in adolescence of a case with agenesis of the corpus callosum

Abstract

Introduction: The corpus callosum is one of the most prominent anatomical structures in the human brain. Its agenesis or absence is infrequent, commonly associated with mental retardation and diagnosed in the first years of life. Objective: To present the clinical case of an adolescent with a late diagnosis of agenesis of the corpus callosum and without mental retardation. Clinical Case: 18-year-old male patient with a personal pathological history of attention deficit hyperactivity disorder and low normal intellectual performance diagnosed since school age. He came to the clinic due to having episodes of loss of consciousness for about 2 months and symptoms suggestive of an adjustment disorder. The physical examination only revealed fascial dysmorphisms. As part of the study, a simple magnetic resonance imaging was performed, which reported agenesis of the corpus callosum. Conclusions: Agenesis of the corpus callosum is a rare and underdiagnosed neurological malformation in adolescence, which should be suspected in the presence of a family history of psychiatric illnesses, facial dysmorphia, and intellectual disability.

Keywords

• adolescente
• agenesia del cuerpo calloso
• diagnóstico tardío.