Nature Communications (Oct 2022)

Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target

  • Heewon Cho,
  • Haw-Young Kwon,
  • Amit Sharma,
  • Sun Hyeok Lee,
  • Xiao Liu,
  • Naoki Miyamoto,
  • Jong-Jin Kim,
  • Sin-Hyeog Im,
  • Nam-Young Kang,
  • Young-Tae Chang

DOI
https://doi.org/10.1038/s41467-022-33526-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 8

Abstract

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Studying the specific roles of macrophage subsets has been hampered by a lack of subset-specific probes. Here the authors report an M1 selective fluorescent probe named CDr17, and demonstrate the suitability of this probe for tracking M1 macrophages in vivo.