Communications Biology (Sep 2022)
Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology
- Bo-yong Park,
- Valeria Kebets,
- Sara Larivière,
- Meike D. Hettwer,
- Casey Paquola,
- Daan van Rooij,
- Jan Buitelaar,
- Barbara Franke,
- Martine Hoogman,
- Lianne Schmaal,
- Dick J. Veltman,
- Odile A. van den Heuvel,
- Dan J. Stein,
- Ole A. Andreassen,
- Christopher R. K. Ching,
- Jessica A. Turner,
- Theo G. M. van Erp,
- Alan C. Evans,
- Alain Dagher,
- Sophia I. Thomopoulos,
- Paul M. Thompson,
- Sofie L. Valk,
- Matthias Kirschner,
- Boris C. Bernhardt
Affiliations
- Bo-yong Park
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Valeria Kebets
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Sara Larivière
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Meike D. Hettwer
- Forschungszentrum Jülich
- Casey Paquola
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Daan van Rooij
- Center for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behavior, Radboud University
- Jan Buitelaar
- Donders Institute for Brain, Cognition and Behaviour, Radboud University
- Barbara Franke
- Donders Institute for Brain, Cognition and Behaviour, Radboud University
- Martine Hoogman
- Donders Institute for Brain, Cognition and Behaviour, Radboud University
- Lianne Schmaal
- Centre for Youth Mental Health, The University of Melbourne
- Dick J. Veltman
- Departments of Psychiatry and Anatomy and Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam
- Odile A. van den Heuvel
- Departments of Psychiatry and Anatomy and Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam
- Dan J. Stein
- SA Medical Research Council Unit on Risk & Resilience in Mental Disorders, Dept of Psychiatry and Mental Health, University of Cape Town
- Ole A. Andreassen
- NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital &Institute of Clinical Medicine, University of Oslo
- Christopher R. K. Ching
- Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California
- Jessica A. Turner
- Department of Psychology and Behavioral Health, The Ohio State University
- Theo G. M. van Erp
- Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine
- Alan C. Evans
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Alain Dagher
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Sophia I. Thomopoulos
- Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California
- Paul M. Thompson
- Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California
- Sofie L. Valk
- Forschungszentrum Jülich
- Matthias Kirschner
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Boris C. Bernhardt
- McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- DOI
- https://doi.org/10.1038/s42003-022-03963-z
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
Individuals across six major psychiatric conditions from the ENIGMA consortium reveals a shared morphological effect, following a sensory-fugal axis, which is related to microstructural gradient and neurotransmitter axes.
