Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach

Mohammad Saeid Nikshoar; Mohammad Ali Khayamian; Saeid Ansaryan; Hassan Sanati; Milad Gharooni; Leila Farahmand; Farshad Rezakhanloo; Keivan Majidzadeh-A; Parisa Hoseinpour; Shahrzad Dadgari; Leila Kiani-M; Mohammad Saqafi; Masoumeh Gity; Mohammad Abdolahad

doi:10.1038/s41467-017-02184-x

Nature Communications (Dec 2017)

Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach

Mohammad Saeid Nikshoar,
Mohammad Ali Khayamian,
Saeid Ansaryan,
Hassan Sanati,
Milad Gharooni,
Leila Farahmand,
Farshad Rezakhanloo,
Keivan Majidzadeh-A,
Parisa Hoseinpour,
Shahrzad Dadgari,
Leila Kiani-M,
Mohammad Saqafi,
Masoumeh Gity,
Mohammad Abdolahad

Affiliations

Mohammad Saeid Nikshoar: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran
Mohammad Ali Khayamian: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran
Saeid Ansaryan: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran
Hassan Sanati: Integrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR
Milad Gharooni: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran
Leila Farahmand: Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR
Farshad Rezakhanloo: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran
Keivan Majidzadeh-A: Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR
Parisa Hoseinpour: Central lab of Pathobiology, Department of Pathology, Breast Cancer Research Center, Motamed Cancer Institute, ACECR
Shahrzad Dadgari: Department of Radiology, Breast Cancer Research Center, Motamed Cancer Institute, ACECR
Leila Kiani-M: Department of Radiology, Breast Cancer Research Center, Motamed Cancer Institute, ACECR
Mohammad Saqafi: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran
Masoumeh Gity: Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences
Mohammad Abdolahad: Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of Tehran

DOI: https://doi.org/10.1038/s41467-017-02184-x
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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Detecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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