MiR-638 repressed vascular smooth muscle cell glycolysis by targeting LDHA

Abstract

Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) accelerated vascular diseases progression, like atherosclerosis and restenosis. MicroRNAs were reported to participate in modulating diverse cellular processes. Here, we focused on exploring the role of miR-638 in VSMCs glycolysis and underlying mechanism.

Keywords

• vsmcs
• mir-638
• pdgf-bb
• proliferation
• migration and invasion
• ldha
• glycolysis