Subcorneal pustular dermatosis in a 7-year old Saudi child: A case report and review of the literature

Abstract

Subcorneal pustular dermatosis (SCPD) also known as Sneddon–Wilkinson disease (Sneddon and Wilkinson, 1956) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence (Johnson and Cripps, 1974). The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis. In this paper we present the case of a 7-years-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Oral and topical corticosteroid has been successfully used in the treatment of the disease.

Keywords

• Subcorneal pustular dermatosis (Sneddon–Wilkinson disease)
• Histopathology
• Immunofluorenscence
• Immunoglobulin A
• Dapsone
• Prednisolone
• Clobetasone proprionate