Influence of the Alternative Sigma Factor RpoN on Global Gene Expression and Carbon Catabolism in Enterococcus faecalis V583

Erica C. Keffeler; Vijayalakshmi S. Iyer; Srivatsan Parthasarathy; Matthew M. Ramsey; Matthew J. Gorman; Theresa L. Barke; Sriram Varahan; Sally Olson; Michael S. Gilmore; Zakria H. Abdullahi; Emmaleigh N. Hancock; Lynn E. Hancock

doi:10.1128/mBio.00380-21

mBio (Jun 2021)

Influence of the Alternative Sigma Factor RpoN on Global Gene Expression and Carbon Catabolism in Enterococcus faecalis V583

Erica C. Keffeler,
Vijayalakshmi S. Iyer,
Srivatsan Parthasarathy,
Matthew M. Ramsey,
Matthew J. Gorman,
Theresa L. Barke,
Sriram Varahan,
Sally Olson,
Michael S. Gilmore,
Zakria H. Abdullahi,
Emmaleigh N. Hancock,
Lynn E. Hancock

Affiliations

Erica C. Keffeler: Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA
Vijayalakshmi S. Iyer: Division of Biology, Kansas State University, Manhattan, Kansas, USA
Srivatsan Parthasarathy: Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA
Matthew M. Ramsey: Department of Ophthalmology, Harvard Microbial Sciences Initiative, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
Matthew J. Gorman: Division of Biology, Kansas State University, Manhattan, Kansas, USA
Theresa L. Barke: Division of Biology, Kansas State University, Manhattan, Kansas, USA
Sriram Varahan: Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA
Sally Olson: Comparative Medicine Group, Kansas State University, Manhattan, Kansas, USA
Michael S. Gilmore: Department of Ophthalmology, Harvard Microbial Sciences Initiative, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
Zakria H. Abdullahi: Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA
Emmaleigh N. Hancock: Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA
Lynn E. Hancock: ORCiD; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA

DOI: https://doi.org/10.1128/mBio.00380-21
Journal volume & issue: Vol. 12, no. 3

Abstract

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Hospital-acquired infections account for 2 billion dollars annually in increased health care expenses and cause more than 100,000 deaths in the United States alone. Enterococci are the second leading cause of hospital-acquired infections.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal