Nature Communications (Dec 2016)

A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy

  • Zhenzhen Wang,
  • Yonghu Sun,
  • Xi’an Fu,
  • Gongqi Yu,
  • Chuan Wang,
  • Fangfang Bao,
  • Zhenhua Yue,
  • Jianke Li,
  • Lele Sun,
  • Astrid Irwanto,
  • Yongxiang Yu,
  • Mingfei Chen,
  • Zihao Mi,
  • Honglei Wang,
  • Pengcheng Huai,
  • Yi Li,
  • Tiantian Du,
  • Wenjun Yu,
  • Yang Xia,
  • Hailu Xiao,
  • Jiabao You,
  • Jinghui Li,
  • Qing Yang,
  • Na Wang,
  • Panpan Shang,
  • Guiye Niu,
  • Xiaojun Chi,
  • Xiuhuan Wang,
  • Jing Cao,
  • Xiujun Cheng,
  • Hong Liu,
  • Jianjun Liu,
  • Furen Zhang

DOI
https://doi.org/10.1038/ncomms13760
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

Read online

Previous studies have shown genetic associations between leprosy and 18 different genes/loci. Here, Wang and colleagues perform genome-wide association study in Han Chinese leprosy patients and describe four novel loci to be associated to the disease.