Nature Communications (Jun 2022)
A calcium-based plasticity model for predicting long-term potentiation and depression in the neocortex
- Giuseppe Chindemi,
- Marwan Abdellah,
- Oren Amsalem,
- Ruth Benavides-Piccione,
- Vincent Delattre,
- Michael Doron,
- András Ecker,
- Aurélien T. Jaquier,
- James King,
- Pramod Kumbhar,
- Caitlin Monney,
- Rodrigo Perin,
- Christian Rössert,
- Anil M. Tuncel,
- Werner Van Geit,
- Javier DeFelipe,
- Michael Graupner,
- Idan Segev,
- Henry Markram,
- Eilif B. Muller
Affiliations
- Giuseppe Chindemi
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Marwan Abdellah
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Oren Amsalem
- Department of Neurobiology, the Hebrew University of Jerusalem
- Ruth Benavides-Piccione
- Instituto Cajal, Consejo Superior de Investigaciones Científicas
- Vincent Delattre
- Laboratory of Neural Microcircuitry, École Polytechnique Fédérale de Lausanne
- Michael Doron
- Edmond and Lily Safra Center for Brain Sciences, the Hebrew University of Jerusalem
- András Ecker
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Aurélien T. Jaquier
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- James King
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Pramod Kumbhar
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Caitlin Monney
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Rodrigo Perin
- Laboratory of Neural Microcircuitry, École Polytechnique Fédérale de Lausanne
- Christian Rössert
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Anil M. Tuncel
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Werner Van Geit
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Javier DeFelipe
- Instituto Cajal, Consejo Superior de Investigaciones Científicas
- Michael Graupner
- Université de Paris, SPPIN - Saints-Pères Paris Institute for the Neurosciences, CNRS
- Idan Segev
- Department of Neurobiology, the Hebrew University of Jerusalem
- Henry Markram
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- Eilif B. Muller
- Blue Brain Project, École Polytechnique Fédérale de Lausanne
- DOI
- https://doi.org/10.1038/s41467-022-30214-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 19
Abstract
The study of learning algorithms in the neocortex requires comprehensive knowledge of synaptic plasticity between its diverse cell types, which is currently lacking. Chindemi et al. describe a modeling approach to fill these gaps in experimental literature, and predict the features of synaptic plasticity in vivo.
