Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration

S. Choayb; H. Adil; Daoud Ali Mohamed; N. Allali; L. Chat; S. El Haddad

doi:10.1155/2021/6633217

Case Reports in Radiology (Jan 2021)

Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration

S. Choayb,
H. Adil,
Daoud Ali Mohamed,
N. Allali,
L. Chat,
S. El Haddad

Affiliations

S. Choayb: Children’s Hospital, Radiology Department, Mohamed V University, Rabat, Morocco
H. Adil: Children’s Hospital, Radiology Department, Mohamed V University, Rabat, Morocco
Daoud Ali Mohamed: Children’s Hospital, Radiology Department, Mohamed V University, Rabat, Morocco
N. Allali: Children’s Hospital, Radiology Department, Mohamed V University, Rabat, Morocco
L. Chat: Children’s Hospital, Radiology Department, Mohamed V University, Rabat, Morocco
S. El Haddad: Children’s Hospital, Radiology Department, Mohamed V University, Rabat, Morocco

DOI: https://doi.org/10.1155/2021/6633217
Journal volume & issue: Vol. 2021

Abstract

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Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). We present a case of an 11 year-old boy presenting extrapyramidal signs and developmental regression. T2-weighted images showed the classic eye of the tiger sign seen in pantothenate kinase-associated neurodegeneration.

Published in Case Reports in Radiology

ISSN: 2090-6862 (Print); 2090-6870 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://onlinelibrary.wiley.com/journal/5370

About the journal