The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis

Abstract

Caspases are well-known drivers of apoptosis, although recent studies suggest potential non-apoptotic functions. Here, McSharry and Beitel show that the Drosophila executioner caspase DrICE regulates endocytic trafficking of key proteins downstream of Hippo during tracheal morphogenesis.