Experimental Gerontology (Aug 2023)

The incidence of acute renal failure and high mortality rate in elderly patients hospitalized with community acquired pneumonia

  • E. Lubart,
  • T. Boguslavsky,
  • G. Goltsman,
  • S. Muhtaseb,
  • A. Matveychuk

Journal volume & issue
Vol. 179
p. 112242

Abstract

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Community acquired pneumonia is associated with high mortality and health care costs, especially in old age. The clinical presentation of pneumonia in the elderly may be asymptomatic or atypical. One of the known complication is an acute kidney injury. The purpose of our study was to estimate the incidence of this complication in elderly patients hospitalized with pneumonia in our geriatric hospital.From a group of 180 elderly patients hospitalized with community-acquired pneumonia 34.4 % developed acute kidney injury. In this group, 51.6 % of patients died compared to 14.4 % in the group of patients without acute kidney injury (p < 0.001). The lower level of e-GFR was significantly associated with mortality (p < 0.001): out of seven patients with e-GFR level of 15–29 mg/mmol, five patients died (71.4 %).Elderly patients with community-acquired pneumonia suffering acute kidney injury experienced worse in-hospital outcomes; mortality rate was significantly higher in our study. We found a relationship between low level of e-GFR and mortality. Clinicians should be alert for early detection and prevention of kidney injury in patients admitted with pneumonia.

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