Nature Communications (Mar 2019)

Anti-quenching NIR-II molecular fluorophores for in vivo high-contrast imaging and pH sensing

  • Shangfeng Wang,
  • Yong Fan,
  • Dandan Li,
  • Caixia Sun,
  • Zuhai Lei,
  • Lingfei Lu,
  • Ting Wang,
  • Fan Zhang

DOI
https://doi.org/10.1038/s41467-019-09043-x
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Fluorophores operating in the second near-infrared window suffer from solvatochromism-caused fluorescence quenching in biological aqueous solution. Here, the authors synthesized a series of pH-responsive pentamethine cyanine fluorophores that afford stable absorption/emission beyond 1000 nm.