Evaluation of Efficient and Practical Methods for the Preparation of Functionalized Aliphatic Trifluoromethyl Ethers

Abstract

The “chlorination/fluorination” technique for aliphatic trifluoromethyl ether synthesis was investigated and a range of products with various functional groups was prepared. The results were compared with oxidative desulfurization-fluorination of xanthates with the same structure.

Keywords

• fluorination
• chlorination
• oxidative desulfurization-fluorination
• antimony trifluoride
• hydrogen fluoride
• trifluoromethyl ethers