A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans

Eszter Bokor; Judit Ámon; Mónika Varga; András Szekeres; Zsófia Hegedűs; Tamás Jakusch; Zsolt Szakonyi; Michel Flipphi; Csaba Vágvölgyi; Attila Gácser; Claudio Scazzocchio; Zsuzsanna Hamari

doi:10.1038/s42003-022-03684-3

Communications Biology (Jul 2022)

A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans

Eszter Bokor,
Judit Ámon,
Mónika Varga,
András Szekeres,
Zsófia Hegedűs,
Tamás Jakusch,
Zsolt Szakonyi,
Michel Flipphi,
Csaba Vágvölgyi,
Attila Gácser,
Claudio Scazzocchio,
Zsuzsanna Hamari

Affiliations

Eszter Bokor: University of Szeged Faculty of Science and Informatics, Department of Microbiology
Judit Ámon: University of Szeged Faculty of Science and Informatics, Department of Microbiology
Mónika Varga: University of Szeged Faculty of Science and Informatics, Department of Microbiology
András Szekeres: University of Szeged Faculty of Science and Informatics, Department of Microbiology
Zsófia Hegedűs: University of Szeged Faculty of Science and Informatics, Department of Microbiology
Tamás Jakusch: University of Szeged Faculty of Science and Informatics, Department of Inorganic and Analytical Chemistry
Zsolt Szakonyi: University of Szeged Faculty of Pharmacy, Institute of Pharmaceutical Chemistry
Michel Flipphi: Institute de Génétique et Microbiologie, Université Paris-Sud
Csaba Vágvölgyi: University of Szeged Faculty of Science and Informatics, Department of Microbiology
Attila Gácser: HCEMM-USZ Fungal Pathogens Research Group, University of Szeged Faculty of Science and Informatics, Department of Microbiology
Claudio Scazzocchio: Section of Microbiology, Department of Infectious Diseases, Imperial College
Zsuzsanna Hamari: University of Szeged Faculty of Science and Informatics, Department of Microbiology

DOI: https://doi.org/10.1038/s42003-022-03684-3
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

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A novel nicotinate degradation pathway is described in Aspergillus nidulans, with metabolic products identified that were not previously found in prokaryotic species. This is the first such pathway to be described in a eukaryote.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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