Recalcitrant giant orf recurrence after amputation: A case report and review of the literature

Abstract

Abstract Orf is caused by a parapoxvirus. We present a recurrent, giant digital orf case in a female patient with a history of hairy cell leukemia. In spite of shave excision, the lesion progressed and recurred after digital amputation. Treatment with topical imiquimod cream and systemic subcutaneous interferon alfa‐2a was successful.

Keywords

• amputation
• ecthyma contagiosum
• imiquimod
• immunocompromised
• interferon alfa‐2a
• nodule