Perbandingan Kombinasi Bupivakain 0,5% Hiperbarik dan Fentanil dengan Bupivakain 0,5% Isobarik dan Fentanil terhadap Kejadian Hipotensi dan Tinggi Blokade Sensorik pada Seksio Sesarea dengan Anestesi Spinal

Abstract

Spinal anesthesia technic has been the technic of choice for caesarean section due to its safety and efficiency compared to general anesthesia. Spinal anesthesia in pregnancy causes hypotension in a heavier and more rapid manner. Hypotension is associated with the height of the sympathetic block influenced by the baricity of the local anesthetics. This study aimed to compare hypotension incidence and sensory blockade height between combination of 12.5 mg 0.5% hyperbaric bupivacaine with 25 µg fentanyl and 12.5 mg 0.5% isobaric bupivacaine with fentanyl 25 µg in spinal anesthesia for caesarean section. The study was performed at the central operating theatre (COT) of Dr. Hasan Sadikin General Hospital during April‒May 2015 using double blind randomized control trial method on 40 patients underwent caesarean section with American Society of Anesthesiologist (ASA) II physical status. The hypotension incidence and sensory blockade height were assessed after spinal anesthesia and measured by t-test, Mann Whitney, and Chi-square tests. Significancy was declared when p value <0.05. The hypotension incidence between the hyperbaric and isobaric groups were 75% vs. 100% (p value=0.017). The mean sensory blockade height was at T6 vs. T4 (p value=0.000). The hypotension incidence and sensory blockade are significantly higher in isobaric 12.5 mg 0.5% bupivacainewith 25 µg fentanyl compared to those in 12.5 mg hyperbaric 0.5% bupivacaine with fentanyl 25 µg.

Keywords

• aesarean section
• hyperbaric bupivacaine
• isobaric bupivacaine
• spinal anesthesia