Effects of polymyxin B on clinical signs, serum TNF-α, haptoglobin and plasma lactate concentrations in experimental endotoxaemia in sheep

Affiliations

Hajimohammadi Ali: Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran
Badiei Khalil: Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran
Kheibari Parviz: Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran
Pourjafar Meherdad: Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran
Chalmeh Aliasghar: Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran

Abstract

The experiment evaluated the effects of intravenous administration of polymyxin B on experimental endotoxaemia in sheep.