Influence of LncRNA NKILA on Biological Behavior of Malignant Tumors and Related Mechanism

ZHAO Yuqiao; LIU Guanglin; WANG Haicun; GAO Xin; JIANG Xingming; LIU Lang

doi:10.3971/j.issn.1000-8578.2022.21.0792

Zhongliu Fangzhi Yanjiu (Jan 2022)

Influence of LncRNA NKILA on Biological Behavior of Malignant Tumors and Related Mechanism

ZHAO Yuqiao,
LIU Guanglin,
WANG Haicun,
GAO Xin,
JIANG Xingming,
LIU Lang

Affiliations

ZHAO Yuqiao: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
LIU Guanglin: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
WANG Haicun: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
GAO Xin: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
JIANG Xingming: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
LIU Lang: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China

DOI: https://doi.org/10.3971/j.issn.1000-8578.2022.21.0792
Journal volume & issue: Vol. 49, no. 1
pp. 67 – 71

Abstract

Read online

NKILA is a kind of newly-discovered lncRNA whose expression is aberrant in diverse malignant tumors. The existing researches have confirmed that NKILA participates in the occurrence and development of tumors mainly by regulating the NF-κB signaling pathway, and has significance to the cancer diagnosis, treatment and prognostic evaluation of patients. This article reviews the abnormal expressions and biological effects of NKILA, and the up- and down-stream mechanisms of NKILA regulating malignant biological behavior in different cancers.

Published in Zhongliu Fangzhi Yanjiu

ISSN: 1000-8578 (Print)
Publisher: Magazine House of Cancer Research on Prevention and Treatment
Country of publisher: China
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://www.zlfzyj.com

About the journal

Abstract

Keywords