Congenericity of Claimed Compounds in Patent Applications

Abstract

A method is presented to analyze quantitatively the degree of congenericity of claimed compounds in patent applications. The approach successfully differentiates patents exemplified with highly congeneric compounds of a structurally compact and well defined chemical series from patents containing a more diverse set of compounds around a more vaguely described patent claim. An application to 750 common patents available in SureChEMBL, SureChEMBLccs and ChEMBL is presented and the congenericity of patent compounds in those different sources discussed.

Keywords

• chemical series
• patent compounds
• similarity analysis
• SureChEMBL
• SureChEMBLccs
• ChEMBL