Prevalence of positive Hepatitis Delta Virus in patients with positive Hepatitis B surface Antigen and its correlative factors in Sari

Abstract

Abstract Background and purpose: Hepatitis Delta Virus (HDV) agent, or HDV, is a defective RNA virus that infects with HBV (Hepatitis B Virus). 15 millions people around the world are infected to HDV. There are different statistics in Iran and other countries about HDV incidence, according to accomplished studies. This study was done for determining HDV incidence in sari and considering its correlative factors.Materials and methods: This study was done in a descriptive procedure on 167 patients. Correlative factors like demographic data and the ways of receiving disorder, history of tattoo, blood transfusion, were multi partner and IV drug abusers were considered. Diagnosing of blood Anti HDV in patients was by ELISA (Enzyme-Linked ImmunoSorbent Assay) way.Results: We couldn’t find any evidences of advantage of HDV in patients. Among 167 HBS-Ag positive subject (63 (%37.7) women and 104 (%62.3) men) were included. Average age of participants was 35.52±14.036. 2 subject had an addiction history (%1.7), 15 subject (%9) had a blood transfusion history, 4 (%2.4) were multipart and 1 (%0.6) had tattoo history and 2 (%1.2) were Prisoners previously.Conclusion: There wasn’t any positive Anti-HDV Ab (Anti- Hepatitis Delta Virus Antibody) in studied patients. It shows that HDV is not endemic in sari. J Mazand Univ Med Sci 2008; 18(67):102-106 (Persian)

Keywords

• Hepatitis D
• hepatitis B
• correlative factors