PLoS ONE (Jan 2021)

Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore-analysis of the SingHealth Diabetes Registry.

  • Liang Feng,
  • Amanda Lam,
  • David Carmody,
  • Ching Wee Lim,
  • Gilbert Tan,
  • Su-Yen Goh,
  • Yong Mong Bee,
  • Tazeen H Jafar

DOI
https://doi.org/10.1371/journal.pone.0259157
Journal volume & issue
Vol. 16, no. 11
p. e0259157

Abstract

Read online

BackgroundAsian populations are at high risk of diabetes and related vascular complications. We examined risk factor control, preventive care, and disparities in these trends among adults with diabetes in Singapore.MethodsThe sample included 209,930 adults with diabetes aged≥18 years from a multi-institutional SingHealth Diabetes Registry between 2013 and 2019 in Singapore. We performed logistic generalized estimating equations (GEEs) regression analysis and used linear mixed effect modeling to evaluate the temporal trends.ResultsBetween 2013 and 2019, the unadjusted control rates of glycated hemoglobin (4.8%, 95%CI (4.4 to 5.1) and low-density lipoprotein cholesterol (LDL-C) (11.5%, 95%CI (11.1 to 11.8)) improved, but blood pressure (BP) control worsened (systolic BP (SBP)/diastolic BP (DBP) ConclusionsTrends in risk factor control improved for glycated hemoglobin and LDL-C, but worsened for BP among diabetic adults in Singapore from 2013 to 2019. Control rates for all risk factors remain inadequate.