Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities

• Dung N. Nguyen,
• Bokai Xu,
• Robyn L. Stanfield,
• Jennifer K. Bailey,
• Satoru Horiya,
• J. Sebastian Temme,
• Deborah R. Leon,
• Celia C. LaBranche,
• David C. Montefiori,
• Catherine E. Costello,
• Ian A. Wilson,
• Isaac J. Krauss

Affiliations

Dung N. Nguyen

Department of Chemistry, Brandeis University, Waltham, Massachusetts, United States

Bokai Xu

Department of Chemistry, Brandeis University, Waltham, Massachusetts, United States

Robyn L. Stanfield

Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States

Jennifer K. Bailey

Department of Chemistry, Brandeis University, Waltham, Massachusetts, United States

Satoru Horiya

Department of Chemistry, Brandeis University, Waltham, Massachusetts, United States

J. Sebastian Temme

Department of Chemistry, Brandeis University, Waltham, Massachusetts, United States

Deborah R. Leon

Department of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts, United States

Celia C. LaBranche

Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States

David C. Montefiori

Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States

Catherine E. Costello

Department of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, Massachusetts, United States

Ian A. Wilson

Department of Integrative Structural and Computational Biology and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States

Isaac J. Krauss

Department of Chemistry, Brandeis University, Waltham, Massachusetts, United States