Comparative Study of the Effects of Pre-emptive Use of Intravenous Lidocaine and Intramuscular Piroxicam on Muscular Pain after Lower Abdominal Surgery under the General Anesthesia

Abstract

Background: Given the importance of pain control after the surgery, and the wide variety of the results of previous researches, this study aimed to compare two methods of intravenous lidocaine and intramuscular piroxicam on postoperative pain in lower abdominal surgery was performed. Methods: In a clinical trial study, 96 patients who were candidates for lower abdominal surgery were randomly divided in three equal groups receiving 2 ml intramuscular normal saline and 5 ml intravenous lidocaine 2%, 2 ml intramuscular piroxicam and 5 ml intravenous normal saline, or 2ml intramuscular and 5 ml intravenous normal saline. 24-hours postoperative pain, the first time of receiving analgesia and the doses of analgesia were compared between the groups. Findings: There was significant difference between the three groups regarding the pain intensity during the first 24 hours after the surgery (P < 0.001). The mean dose of used analgesia showed significant difference between the normal saline (92.19 ± 42.20 mg), lidocaine (89.69 ± 45.00 mg) and piroxicam (80.00 ± 40.60 mg) groups (P < 0.001). The first time of receiving analgesia and duration of staying in the recovery room were significantly difference between the groups. Normal saline group had the shortest first time of receiving analgesia and the longest time of recovery staying. The first time of receiving analgesia was shorter in lidocaine group than the piroxicam group. Conclusion: The results prescribe piroxicam in patients undergoing lower abdominal surgery to reduce the severity of pain after the operation. It can be suggested to use piroxicam as a safe medication to reduce pain after lower abdominal surgeries.

Keywords

• Post-operative pain
• Lidocaine
• Piroxicam