Clinico-epidemiological profile of SARS-CoV-2 infection in individuals investigated at tertiary care hospital

Abstract

Background: The World Health Organization (WHO) declared the pandemic disease caused by SARS-CoV-2 as coronavirus disease 2019 (COVID-19). Presently, COVID-19 has infected individuals in over seventy nations across the world. China had a significant COVID-19 impact and taken great measures to restrict the disease's development and increase the cure rate. Objective: Research paper describes the clinico-epidemiological profile of SARS-CoV-2 infection in individuals tested at state key Virology Research and Diagnostic Laboratory (VRDL), Pt. J.N.M. Medical College, Raipur (CG), India. Method: Respiratory samples oropharyngeal and nasopharyngeal swabs were collected in VTM from suspected COVID-19 individuals for laboratory analysis and cases were confirmed by reverse transcription polymerase chain reaction (RT-PCR). A total of 32,145 patients with confirmed diagnosis of SARS-CoV-2 infection were included in this study. Data included in this study, from the period of August 2020 to February 2021, were collected from offline and online medical records. Result: Amongst 32,145 SARS-CoV-2 infected patients, 19674 (61%) were males and 12471 (39%) were females, 5756 (17.90%) were symptomatic and 26,389 (82.10%) were asymptomatic. Maximum percentage of symptomatic subjects were found in 70-79 years (25%) followed by 60-69 years (24%), out of 5756 symptomatic patients 3772 (65.53%) were males and 1984 (34.46%) were females, most common presenting symptom was cough (80.9%) followed by fever (33.8%), sore throat (16.1%) breathlessness (14.1%). The most common comorbidity found among symptomatic group was hypertension followed by diabetes. Conclusion: COVID-19 is an evolving disease and data from our study help in understanding the clinic-epidemiological profile of patients.

Keywords

• sars-cov-2
• clinico-epidemiological
• rt-pcr
• covid-19