A tutorial on how not to over-interpret STRUCTURE and ADMIXTURE bar plots

Daniel J. Lawson; Lucy van Dorp; Daniel Falush

doi:10.1038/s41467-018-05257-7

Nature Communications (Aug 2018)

A tutorial on how not to over-interpret STRUCTURE and ADMIXTURE bar plots

Daniel J. Lawson,
Lucy van Dorp,
Daniel Falush

Affiliations

Daniel J. Lawson: University of Bristol, Integrative Epidemiology Unit, Population Health Sciences
Lucy van Dorp: University College London Genetics Institute (UGI), University College London
Daniel Falush: Milner Centre for Evolution, University of Bath

DOI: https://doi.org/10.1038/s41467-018-05257-7
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 11

Abstract

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Clustering methods such as STRUCTURE and ADMIXTURE are widely used in population genetic studies to investigate ancestry. Here, the authors provide a tutorial on how to interpret results of these analyses and a tool to test the goodness of fit of the model.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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