Romanian Journal of Internal Medicine (Sep 2024)

Association of combined −344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population

  • Nouhi Youssef,
  • Aboubakr Fatima-Zahrae,
  • Brini Otmane El,
  • Benazzouz Bouchra,
  • Akhouayri Omar

DOI
https://doi.org/10.2478/rjim-2024-0011
Journal volume & issue
Vol. 62, no. 3
pp. 323 – 330

Abstract

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Background: Aldosterone synthase (CYP11B2) is crucial for aldosterone production, and variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This study explores the link between two single nucleotide polymorphisms (SNPs) in the CYP11B2 gene - −344T/C and K173R and T2DM in the Moroccan population .

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