Brazilian Journal of Oncology (Oct 2021)
Implementing somatic mutation testing in clinical setting: recommendations from a panel of experts
- Vladmir Cláudio Cordeiro-de-Lima,
- Luiz Henrique Araújo,
- Bernardo Garicochea,
- Vanderson Rocha,
- Max Mano,
- William Nassib William,
- Aline Lauda Freitas Chaves,
- Gustavo dos Santos Fernandes,
- Angelica Nogueira-Rodrigues,
- Denis Leonardo Jardim,
- Andreia C Melo,
- Celso Abdon Mello,
- Clarissa Serodio Baldotto,
- Mauro Zukin,
- Aknar Calabrich,
- Ana Gelatti,
- Gilberto deCastro,
- Thiago Bueno de-Oliveira,
- Markus Gifoni,
- Williams Barra,
- Anelisa K. Coutinho,
- Renata D’Alpino Peixoto,
- Carla Rameri de-Azevedo,
- Eduardo Paulino,
- José Bines,
- Romualdo Barroso,
- Daniel Gimenes,
- Rafael Aliosha Kaliks,
- Andre Poisl Fay,
- Diogo Bugano,
- Pedro Isaacsson,
- Carlos Chiattone,
- Jorge Vaz,
- Guilherme Duffles,
- Otavio Baiocchi,
- Rafael Schmerling,
- Rodrigo Ramela Munhoz,
- Rodrigo Guedes,
- Olavo Feher,
- Camilla Akemi Felizardo Yamada,
- Carolina Fittipaldi,
- Clarissa Maria de Cerqueira Mathias,
- Renan Orsati Clara,
- Alesssandro Leal
Affiliations
- Vladmir Cláudio Cordeiro-de-Lima
- ORCiD
- Instituto do Câncer do Estado de São Paulo (ICESP), Department of Medical Oncology - São Paulo - SP - Brazil
- Luiz Henrique Araújo
- Instituto Nacional de Câncer (INCA), Department of Medical Oncology - Rio de Janeiro - RJ - Brazil
- Bernardo Garicochea
- Centro Paulista de Oncologia (CPO), Grupo Oncoclínicas, São Paulo - SP - Brazil
- Vanderson Rocha
- Instituto do Câncer do Estado de São Paulo (ICESP), Department of Medical Oncology - São Paulo - SP - Brazil
- Max Mano
- Centro Paulista de Oncologia (CPO), Grupo Oncoclínicas, São Paulo - SP - Brazil
- William Nassib William
- Hospital Beneficência Portuguesa (BP) de São Paulo, Department of Medical Oncology - São Paulo - SP - Brazil
- Aline Lauda Freitas Chaves
- DOM Oncologia, Divinópolis - MG - Brazil
- Gustavo dos Santos Fernandes
- Hospital Sírio-Libanês (HSL) de Brasília, Department of Medical Oncology - Brasília - DF - Brazil
- Angelica Nogueira-Rodrigues
- Sociedade Brasileira de Oncologia Clínica, São Paulo - SP - Brazil
- Denis Leonardo Jardim
- Hospital Sírio-Libanês de São Paulo, Department of Medical Oncology - São Paulo - SP - Brazil
- Andreia C Melo
- Instituto Nacional de Câncer (INCA), Department of Medical Oncology - Rio de Janeiro - RJ - Brazil
- Celso Abdon Mello
- A. C. Camargo Cancer Center, Department of Medical Oncology - São Paulo - SP - Brazil
- Clarissa Serodio Baldotto
- Oncologia D’Or Rio de Janeiro, Rede D’Or, Rio de Janeiro - RJ - Brazil
- Mauro Zukin
- Oncologia D’Or Rio de Janeiro, Rede D’Or, Rio de Janeiro - RJ - Brazil
- Aknar Calabrich
- Clínica de Assistência Multidisciplinar em Oncologia (AMO), Salvador - BA - Brazil
- Ana Gelatti
- Grupo Oncoclínicas Porto Alegre, Porto Alegre - RS - Brazil
- Gilberto deCastro
- Instituto do Câncer do Estado de São Paulo (ICESP), Department of Medical Oncology - São Paulo - SP - Brazil
- Thiago Bueno de-Oliveira
- A. C. Camargo Cancer Center, Department of Medical Oncology - São Paulo - SP - Brazil
- Markus Gifoni
- Universidade Federal do Ceará, Fortaleza - CE - Brazil
- Williams Barra
- Faculdade de Medicina, Universidade Federal do Pará, Department of Medical Oncology - Belém - PA - Brazil
- Anelisa K. Coutinho
- Clínica de Assistência Multidisciplinar em Oncologia (AMO), Salvador - BA - Brazil
- Renata D’Alpino Peixoto
- Centro Paulista de Oncologia (CPO), Grupo Oncoclínicas, São Paulo - SP - Brazil
- Carla Rameri de-Azevedo
- Instituto de Materno-Infantil de Pernambuco (IMIP), Recife - PE - Brazil
- Eduardo Paulino
- Instituto Nacional de Câncer (INCA), Department of Medical Oncology - Rio de Janeiro - RJ - Brazil
- José Bines
- Instituto Nacional de Câncer (INCA), Department of Medical Oncology - Rio de Janeiro - RJ - Brazil
- Romualdo Barroso
- Hospital Sírio-Libanês (HSL) de Brasília, Department of Medical Oncology - Brasília - DF - Brazil
- Daniel Gimenes
- Centro Paulista de Oncologia (CPO), Grupo Oncoclínicas, São Paulo - SP - Brazil
- Rafael Aliosha Kaliks
- Sociedade Brasileira de Oncologia Clínica, São Paulo - SP - Brazil
- Andre Poisl Fay
- Escola de Medicina da Pontífica Universidade Católica do Rio Grande do Sul (PUC-RS), Porto Alegre - RS - Brazil
- Diogo Bugano
- Hospital Israelita Albert Einstein (HIAE), Department of Medical Oncology - São Paulo - SP - Brazil
- Pedro Isaacsson
- Hospital Moinho de Vento, Department of Medical Oncology - Porto Alegre - RS - Brazil
- Carlos Chiattone
- Faculdade de Medicina da Santa Casa de Misericórdia do São Paulo, Department of Hematology - São Paulo - SP - Brazil
- Jorge Vaz
- Instituto CETTRO, Brasília - DF - Brazil
- Guilherme Duffles
- Universidade de Campinas, Faculdade de Medicina, Department of Hematology - Campinas - SP - Brazil
- Otavio Baiocchi
- Universidade Federal do estado de São Paulo (UNIFESP), Department of Hematology - São Paulo - SP - Brazil
- Rafael Schmerling
- Hospital Beneficência Portuguesa (BP) de São Paulo, Department of Medical Oncology - São Paulo - SP - Brazil
- Rodrigo Ramela Munhoz
- Instituto do Câncer do Estado de São Paulo (ICESP), Department of Medical Oncology - São Paulo - SP - Brazil
- Rodrigo Guedes
- Oncologia D’Or Bahia, Rede D’Or, Salvador - BA - Brazil
- Olavo Feher
- Instituto do Câncer do Estado de São Paulo (ICESP), Department of Medical Oncology - São Paulo - SP - Brazil
- Camilla Akemi Felizardo Yamada
- ORCiD
- Hospital Beneficência Portuguesa (BP) de São Paulo, Department of Medical Oncology - São Paulo - SP - Brazil
- Carolina Fittipaldi
- Instituto Nacional de Câncer (INCA), Department of Medical Oncology - Rio de Janeiro - RJ - Brazil
- Clarissa Maria de Cerqueira Mathias
- Sociedade Brasileira de Oncologia Clínica, São Paulo - SP - Brazil
- Renan Orsati Clara
- Sociedade Brasileira de Oncologia Clínica, São Paulo - SP - Brazil
- Alesssandro Leal
- ORCiD
- Hospital Israelita Albert Einstein (HIAE), Department of Medical Oncology - São Paulo - SP - Brazil
- DOI
- https://doi.org/10.5935/2526-8732.20210019
- Journal volume & issue
-
Vol. 17,
no. 00
Abstract
There has been a rapid increase in the volume of genomic data gathered from different cancers, this has helped to develop new tumor classifications as well as to select better tailored therapies for the patients. Some of the genomic markers identified are also prognostic and predictive factors. Additionally, many technologies have been used to investigate these alterations, each with different benefits and caveats. The Genomics Committee from the Sociedade Brasileira de Oncologia Clínica (SBOC) put together a group of specialists, from different regions of Brazil that work both in the private and public scenario, to gather and organize the information regarding the utility of somatic mutation testing in solid tumors. This special article summarizes their recommendations on how to better incorporate this information into clinical practice.
Keywords
