Molecules (Apr 2017)

The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions

  • Ya Zhou,
  • Zhiqing Liu,
  • Tingting Yuan,
  • Jianbin Huang,
  • Chenjiang Liu

DOI
https://doi.org/10.3390/molecules22040576
Journal volume & issue
Vol. 22, no. 4
p. 576

Abstract

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A facile, green, and efficient method for the direct oxidative amination of benzoxazoles using heterocyclic ionic liquid as catalyst has been developed. The reaction proceeded smoothly at room temperature and gave the desirable 2-aminobenzoxazoles with good to excellent yields (up to 97%). The catalyst 1-butylpyridinium iodide can be easily recycled and reused with similar efficacies for at least four cycles.

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