Nature Communications (Jan 2023)
A population-based matched cohort study of major congenital anomalies following COVID-19 vaccination and SARS-CoV-2 infection
- Clara Calvert,
- Jade Carruthers,
- Cheryl Denny,
- Jack Donaghy,
- Lisa E. M. Hopcroft,
- Leanne Hopkins,
- Anna Goulding,
- Laura Lindsay,
- Terry McLaughlin,
- Emily Moore,
- Bob Taylor,
- Maria Loane,
- Helen Dolk,
- Joan Morris,
- Bonnie Auyeung,
- Krishnan Bhaskaran,
- Cheryl L. Gibbons,
- Srinivasa Vittal Katikireddi,
- Maureen O’Leary,
- David McAllister,
- Ting Shi,
- Colin R. Simpson,
- Chris Robertson,
- Aziz Sheikh,
- Sarah J. Stock,
- Rachael Wood
Affiliations
- Clara Calvert
- Usher Institute, University of Edinburgh
- Jade Carruthers
- Public Health Scotland
- Cheryl Denny
- Public Health Scotland
- Jack Donaghy
- Public Health Scotland
- Lisa E. M. Hopcroft
- Public Health Scotland
- Leanne Hopkins
- Public Health Scotland
- Anna Goulding
- Public Health Scotland
- Laura Lindsay
- Public Health Scotland
- Terry McLaughlin
- Public Health Scotland
- Emily Moore
- Public Health Scotland
- Bob Taylor
- Public Health Scotland
- Maria Loane
- Institute of Nursing and Health Research, Ulster University
- Helen Dolk
- Institute of Nursing and Health Research, Ulster University
- Joan Morris
- Population Health Research Institute, St George’s, University of London
- Bonnie Auyeung
- School of Philosophy, Psychology and Language Sciences, University of Edinburgh
- Krishnan Bhaskaran
- Department of Non-Communicable Diseases Epidemiology, London School of Hygiene and Tropical Medicine
- Cheryl L. Gibbons
- Public Health Scotland
- Srinivasa Vittal Katikireddi
- Public Health Scotland
- Maureen O’Leary
- Public Health Scotland
- David McAllister
- School of Health & Wellbeing, University of Glasgow
- Ting Shi
- Usher Institute, University of Edinburgh
- Colin R. Simpson
- Usher Institute, University of Edinburgh
- Chris Robertson
- Public Health Scotland
- Aziz Sheikh
- Usher Institute, University of Edinburgh
- Sarah J. Stock
- Usher Institute, University of Edinburgh
- Rachael Wood
- Usher Institute, University of Edinburgh
- DOI
- https://doi.org/10.1038/s41467-022-35771-8
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 11
Abstract
The risks of major congenital anomalies associated with SARS-CoV-2 vaccination in early pregnancy are not well understood. Here, the authors conduct a population-based cohort study using electronic health records from Scotland and find no evidence of an association, supporting vaccine safety in pregnancy.