Tropical Medicine and Infectious Disease (Jan 2024)

Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review

  • Arwa A. Al-Qahtani,
  • Fatimah S. Alhamlan,
  • Ahmed Ali Al-Qahtani

DOI
https://doi.org/10.3390/tropicalmed9010013
Journal volume & issue
Vol. 9, no. 1
p. 13

Abstract

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Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress excessive inflammation and promote tissue repair. Here, we provide a comprehensive overview of the role of pro-inflammatory and anti-inflammatory ILs in infectious diseases, with a focus on the mechanisms underlying their effects, their diagnostic and therapeutic potential, and emerging trends in IL-based therapies.

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