Canadian Journal of Infectious Diseases and Medical Microbiology (Jan 2014)

Micafungin Compared with Caspofungin for the Treatment of Febrile Episodes in Neutropenic Patients with Hematological Malignancies: A Retrospective Study

  • Sarah Shalhoub,
  • Luchen Wang,
  • Arthur Ching,
  • Shahid Husain,
  • Coleman Rotstein

DOI
https://doi.org/10.1155/2014/983724
Journal volume & issue
Vol. 25, no. 6
pp. 299 – 304

Abstract

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BACKGROUND: Invasive fungal infections are associated with morbidity and mortality in neutropenia secondary to hematological malignancies. Empirical antifungal agents are used to reduce their consequences. Caspofungin is the only echinocandin approved for this indication. Micafungin was compared with caspofungin for the treatment of patients with hematological malignancies and prolonged neutropenia.